Relationship between CRISPR-Cas9 and Stem Cells - Free Essay Example

Sample details Pages: 7 Words: 2151 Downloads: 2 Date added: 2019/06/26 Category Biology Essay Level High school Tags: Stem Cell Essay Did you like this example? Have you ever wondered if it is possible to cure cancer, have genetically related babies from same-sex parents, completely eradicate mosquitoes, resurrect an extinct species, or even insert a GIF into bacteria and have the bacteria replicate the GIF? With technology becoming more advanced by the hour, increasing possibilities are arising. In 1993, certain segments of DNA were discovered, called CRISPR (Clusters of Regularly Interspaced Short Palindromic Repeats). Twelve years later, Cas9, an enzyme responsible for separating areas of DNA was discovered. Don’t waste time! Our writers will create an original "Relationship between CRISPR-Cas9 and Stem Cells" essay for you Create order Used together, it is called the CRISPR-Cas9 system. The CRISPR-Cas9 system is definitely capable of benefiting the human race by slowly filtering out the unwanted or undesired traits or diseases in the gene pool that will hinder the human race by slowly spreading throughout the gene pool, if not filtered and avoided. Along with CRISPR-Cas9, there appears to be certain cells called stem cells, which are types of cells that are multi-functional and, naturally, have the power to develop into any type of cell that is necessary, depending on and given the situation. Furthermore, CRISPR-Cas9 and stem cell research are the absolute tipping point for breakthroughs in biology to come. CRISPR is a repeated pattern, most of the time found in prokaryotic organisms, that guides RNA to certain sequences of DNA. Cas9 is an enzyme that is in a position to cut DNA using a guide RNA. CRISPR-Cas9 will attach itself to a certain segment of DNA found by the guide RNA partnered along with the CRISPR-Cas9 enzyme. CRISPR-Cas9 literally cuts the DNA so that the other DNA can be inserted or so the DNA can heal itself leaving the harmful mutation or section of DNA behind. By using CRISPR-Cas9 and the natural technologies it provides to us, we can filter out many undesired traits or diseases that hinder our gene pool, especially those which cause certain fatalities or make life far near impossible for not only the victim of the disease or trait but the families of that individual person, too. Many people have been incorporating CRISPR-Cas9 into their lives for nearly the past 10 years and have no knowledge of the technology or aspect it plays in their lives. CRISPR-Cas9 has been and can be used in many different ways; such as, the fact that it is used to enhance the shelf-life of many yogurts and cheeses that are sold to the public in commercial-sized quantities (Grens, Kerry. There is CRISPR in Your Yogurt.). The improved resistance of the cultures pertains to foreign bacteria and possible viruses. Not only does CRISPR-Cas9 improve the shelf-life of certain foods, but it also reduces the risk of getting people sick, which in turn saves a lot of money. Sicknesses like malaria are a global burden, but fear not, CRISPR-Cas9 can also be used to progressively eradicate the population of a few certain species of mosquitoes on the earth. Scientists have recently located a female infertility gene that will spread down to other female mosquitoes, rendering them infertile. CRISPR-Cas9 will latch itself on to the female infertility gene (Molteni, Megan. Heres the Plan to End Malaria With Crispr-Edited Mosquitoes.) And then, with human effort will be transported to another female mosquitoes genes. Over time, the population of harmful mosquitoes will become extinct, saving thousands maybe even hundreds of thousands of people. Although this may sound like a solid idea, the ethical side of the notion is not solid, at all. There seems to be many people that say that its outright wrong to eradicate an entire species of animal, no matter what situation it is under. Many other people disagree, bringing up the rhetoric that mosquitoes carry malaria and malaria kills thousands a day. Eradicating harmful mosquitoes has been discussed by multiple African leaders as of Monday 7 July 2018, with a project called Zero Starts with Me (African leaders launch new, continent-wide campaign for a malaria-free Africa Zero Malaria Starts with Me campaign empowers Africans to take a stand in the fight against the deadly disease). The UN nearly unanimously decided against a moratorium that would ban gene drives on a few species of mosquitoes (Matthews, Dylan. Gene Drives Could End Malaria. And They Just Escaped a UN Ban.). Right now, a group called Target Malaria, is working on a project similar to what had been earlier discussed (Matthews, Dylan. Gene Drives Could End Malaria. And They Just Escaped a UN Ban.). Once the gene drive is released into the wild, thousands of lives will be saved, and the malaria threat will become less intimidating. Now to the other key, stem cells, are an unspecialized cell that has the ability to form itself into any type of cell, given the situation that it is in. The earliest mention of stem cells dates back to 1868 (Bostons Childrens Hospital) in German biologist Ernst Haeckels papers with the German term Stammzelle (translates to stem cell). Stem cells have been used in countless procedures with the goal of curing once incurable diseases, Such as sickle cell anemia. According to the Fetal Treatment Center (UCSF Fetal Treatment Center.), sickle cell anemia is treatable using what is called stem cell therapy (UCSF Fetal Treatment Center.). Sickle cell anemia is an inheritable disease that causes red blood cells to break down causing blood blockage and/or pain in the hosts body, and in even some rare cases cause death. Using the modern technology that we have today and all of the acceptance of stem-cell therapy, infants can avoid the aggravatingly painful disease and avoid passing it down to their children. People who have already lived with the disease for an extended period of time can be cured of sickle cell anemia, eliminating a possibly infinite amount of pain. How stem cell therapy for sickle cell anemia works is by replacing the native cells in some persons body that produce red blood cells, these cells are called hematopoietic stem cells, with new cells. This leads to the termination of some persons body producing sickle cells, the cells t hat are produced by sickle cell anemia that causes the aggravating pain. Within the procedure, a doctor will begin to transfer healthy stem cells from a donors bone marrow to some persons body by an injection from an IV tube into one of some persons veins. When the stem cells are all inside of some persons body, theyll head over to some persons native bone marrow and will commence creating healthy blood cells. A majority of the people in the United States of America believe that stem cell research is morally acceptable. According to a Gallup news poll (Gallup, Inc. , Stem Cell Research.), out of an unspecified number of people, nearly 66% of people polled approve of stem cell research and believe that its morally acceptable, 29% of people polled did not approve and found it morally unacceptable, 2% of the people polled believed that it depended on the situation, and 3% of people polled had absolutely no opinion on it, whatsoever. Gallup had recorded this survey over a lengthy span of 16 years, from 2002 until 2018. Along with that, The numbers have started to differ greatly with acceptance in favor. Most likely, in the future, stem cells will be the most accepted way of treating diseases and abnormalities throughout the human body. Most people throughout European countries have really shown acceptance according to a variety of articles, so accepted to the point where there is even commercial stem-cell based treatment to regenerate damaged ocular system called Holoclar. After 20 years of studies, experiments, and trial, it was finally accepted in Europe. (Europe Approves Holoclar? ®, the First Stem Cell-Based Medicinal Product., Eurostemcell.) Despite these positive views of stem cell research and treatment There seems to be several flaws in the system. Stem cell therapy, according to Dr. Marvin M. Lipman, M.D., should be low cost and if not, virtually free. (Interlandi, Janeen. The Trouble with Stem Cell Therapy) The FDA, explicitly advises people to be very cautious when considering stem cell therapy for an ailment, the FDA also has the power to regulate the systems in which different types of stem cell therapies, treatments, enhancements, and etc., run through. They also advise customers of stem cell treatments to warn the FDA of adverse reactions they had experienced from the usage of the variety of stem cell treatments including, for cancer treatments, the growth of malignant or even benign tumors, as malignant ones can be fatal and benign ones can be costly and hindering. Other advisories from the FDA contain asking the vendor of the stem cell if they have been reviewed and approved by the FDA for treatment and also to ask for an explanation from the vendor to what to the customer of the treatment doesnt understand (Office of the Commissioner. Consumer Updates FDA Warns About Stem Cell Therapies.). Although, stem-cell research has its negatives, many people have claimed that stem-cell treatments have thoroughly improved their lives. According to Kevin Punsky, a controlled study on stem-cell therapy effectiveness on arthritis, found that stem-cell therapy greatly improved the effects of arthritis on those affected with it. Even the placebos seemed to cause relief from pain, too. The two conclusions from the study that was conducted by Mayo Clinic were that; stem cell injections did work and provide pain relief and that it is possible that injections of anything can cause pain relief. Another benefit of stem cell research is that Gay and Lesbian couples will be in a position to have biologically related children to both parents. They will also feel less alienated from society as time goes on and as stem cell babies become more common. Using haploid (contains only half of the information) embryonic stem cells, researchers in china were in a position to successfully create healthy mice from two mothers that went on to have children of their own. According to Victoria Forster of Forbes ( Forster, Victoria. Researchers Have Created Healthy Mice From Same-Sex Parents. But Why?), Chinese researchers were in a position to produce healthy offspring from two mothers. The offspring also went on to have healthy babies, too. Although they did try creating offspring with two male mice and a surrogate mother, it did not work out nearly as well, and therefore, the babies died shortly after birth. The reason for this happening was due to the cause of imprints. Imprinting is the process of inheriting certain genes, one from the father and one from the mother. To create the mice offspring using two mothers, the scientists had to cut out a few imprints, using CRISPR-Cas9, but with the male mice and their offspring the scientists had to cut out several imprints, again, using the CRISPR-Cas9 system. Even with all those imprints cut out of the male mice, the babies were still, born unhealthy, which led the scientists and their team to search for the hindering imprint and/or imprints that caused the hindrance in the health development of the mice which were born from two fathers and a surrogate mother. ( Forster, Victoria. Researchers Have Created Healthy Mice From Same-Sex Parents. But Why?) Using this method may even be possible in humans, according to journalist, Julie Compton of NBC News. Referencing the experiment with creating mice offspring with two mothers and two fathers, the article discussed how same-sex couples, sometime in the future, will be in a position to have children with both of their parents DNA (Compton, Could Same-Sex Couples Soon Conceive a Child with Both Their DNA?). In the second part of the article, Compton, in-depth, discusses the social implications and the legal implications given that, in some states, the processes of having babies via donors is still uncertain in quite a few states (Compton, Could Same-Sex Couples Soon Conceive a Child with Both Their DNA?). Using the method of biologically related same-sex parents, the courts will have no other choice than to assign legal parenthood to the same-sex couple, given that a problem arises related to custody. CRISPR-Cas9 and Stem Cell research has provided so many groundbreakers and breakthroughs in the field of biology. As previously stated, people have been incorporating the CRISPR-Cas9 into their lives for the past 10 years with not even a trace of a clue. Yogurt and cheeses have been altered with the system. It saves many lives and inadvertently saves everyone involved in the business so much money. Not only have we found a cure for a once-incurable disease called sickle cell anemia which is agonizingly painful and carried down through generations, weve also found a way to progressively eradicate an entire population of malaria-carrying mosquitoes that currently kill thousands a day, weve even found a way to produce offspring from biologically same sex parents in mice. What was once thought of, as science fiction, is becoming non-fiction. In order for us, as humans, to evolve, we need to take advantage of what CRISPR-Cas9 research and stem cell research has to offer.

Reported News on Best Persuasive Essay Topics Discovered

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Fraud, Deceptions, and Downright Lies About Ivey Mba Essay Samples Exposed

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Finding Easy English Research Paper Topics

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Essay Examples For Placement Test

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Essay about The Fight Against Child Pornography - 2339 Words

In recent years, pornography has established itself as perhaps the most controversial topic arising out of the use of the Internet. The easy availability of this type of sexually explicit material has caused a panic among government officials, family groups, religious groups and law enforcement bodies and this panic has been perpetuated in the media. One of the unique challenges to regulating or settling on the appropriate way to regulate is that there is no concrete definition of pornography. While law enforcement bodies such as the police, prosecutors and judges, are accustomed to dealing with issues that are exclusive to the United States, the Internet is a worldwide community with servers and members coming†¦show more content†¦The second real issue is finding a way to regulate and enforce the removal of material that is agreed upon as being inappropriate for anyone to have on the Internet. I am specifically touching on the issue of child pornography. While it is illegal in the United States, as it is in many countries, government and law enforcement officials are having a difficult time catching offenders who post this type of material. So with this type of problem concerning pornography this issue is not deciding on appropriate means of regulation, but rather how to enforce the regulation already in pla ce. It is obvious that for years, the government has been trying to regulate this type of content but has seen very limited success. Part of the reason for this is because certain regulatory actions intended to protect only a small group, such as children, should not require the prohibition of material that adults have access to in other arenas. It is for example, legal for people to rent pornographic movies or buy nude magazines, so distribution of this type of material on the Internet should not be completely limited. 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We really need to fight with this problem because is ending with our teenager liberty, social moral and is creating hires crimes. â€Å"It is estimated that there are 60 million survivors of juvenile sexual abuse in America today. Child abuse contributes to our overcrowded prisons as nearly 31% of woman in prison say they were abuse as juvenile† (pat Lunsford). Is true that many

Compare and Contrast Call of the Wild Book and Movie free essay sample

Buck lives in Judges Millers estate at the beginning of both the book and the movie. He is then kidnapped by Manuel, the gardener. He is sold to dog salesmen heading to Alaska. He is disciplined by the Law of Club and Fang. The man in the red sweater takes Buck out of the cage and repeatedly beats him. Buck continues to try to attack until he is to week to fight. He then learns the law of Club and Fang. Buck is sold and put on a sled team. He learns to dig a hole in the snow to stay warm. He has a fierce rivalry with the lead dog Spitz. Spitz then kills one of Buck’s best friends Curly by ripping Curly’s face up. Buck ends up having multiple fights with Spitz. One of which where Spitz takes Buck sleeping hole and tries to keep it. Spitz gets whipped and sent back to his own hole. We will write a custom essay sample on Compare and Contrast: Call of the Wild Book and Movie or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page Buck and Spits end up in a fight in which Buck is determined to kill Spitz and end the rivalry for good. He then does what he was determined to do and kills Spitz. Buck then takes the lead dog position and gains trust from his team. The team is then taken over by Hal, Charles, and Mercedes. They are amateur sled runners and don’t quite know what they are doing. They end up shooting a dog (Dave), because he was too weak to go on. Buck then leads the team into John Thornton’s little camp setup. Hal was advised by John not to go across the ice but he decides to do it anyway. Hal starts beating Buck and John Thornton threatens to kill him with his rifle. John then takes Buck to be his own. They all fall through, including the team. They are killed and John takes care of Buck, the only survivor. Buck then saves john Thornton’s life a couple times. John and Buck develop a special bond. John decides to search for gold. Buck is in part of a bet made by john Thornton that says he can pull a sled with a fairly large amount of weight. Buck then shocks everybody and pulls the sled 100 yards and wins John Thornton $1000 ($1600 in the book). John is out in the search of gold. He comes across a Yeehat tribe and builds up hate for them. Buck scares away the Yeehats once. They the com back later and kill John Thornton by shooting him with a bow and arrow. Buck then kills multiple Yeehats out of anger. He is then left with the decision to live by himself in the wild. Differences In the movie, Buck was never sold to Francois and Perrault. He was never a part of their team and he did not steal any bacon from Francois. In the movie, Buck started out going to John Thornton’s team, stolen by Black Burtons bandits, claimed by a dog auctioneer, sold to Hal and his crew, brought across Johns Thornton’s camp and is returned to him. Buck was never sold from Francois and Perrault to a Scotch half-breed man that was very hairy. It did not tell the names of other dogs in the movie. In my eyes, the movie portrayed John Thornton’s friend, Pete, more than in the book. In the movie John Thornton is attracted to a girl at a bar. A man named Black Burton doesn’t like John so he has his team stolen by some of his thugs. They then take the team to a town. On the way a man falls down a hill and is killed. When the dogs get to the town, the only guy left on the sled is frozen solid and killed. A man then claims the dogs on the spot and auctions them off to Hal, Charles, and Mercedes. They plan to take the team to Dawson city (where John Thornton is). On the way a dog (Dave) is shot by Hal because he can’t go on. They come across John Thornton’s camp. John takes Buck back and the others drowned. John then takes more care of buck and heals him up. The book stated that Buck had killed a Moose by wearing it out and then attacking it. That never happened in the movie. In the book, Mad Dolly was a dog that raged and tried to kill Buck. The movie showed Mad Dolly as a horse. The movie shows more dialect and perspective of john Thornton rather than Buck. It made the movie almost more about John than it did about Buck. John and Buck found a cabin in the woods that had a gun in it that said E. K. W. on it. That wasn’t in the book. Because of all of the similarities and differences that I have written, I believe that the book was way better than the movie. The movies didn’t have much anything that was the same in the book. The worst part was that it left me guessing about who E. K. W. was. It didn’t even give a hint about who he or she was. That should not ever happen in a movie.